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The IVW method revealed no strong causal association between VEGF and any ischemic stroke (odds ratio [OR] 1.01, 95% CI 0.991.04, p = 0.39), cardioembolic stroke (OR 1.04, 95% CI 0.971.12, p = 0.28), large-artery stroke (OR 1.02, 95% CI 0.951.09, p = 0.62), and small-vessel stroke (OR 0.98, 95% CI 0.911.04, p = 0.46)

A predefined drop-out level was estimated to be about 15%

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